Vitiligo Repigmentation with Melanoma Progression During Pembrolizumab Treatment
نویسندگان
چکیده
منابع مشابه
Vitiligo Repigmentation: What’s New?
Vitiligo is a relatively common acquired skin disorder, characterized by the progressive loss of melanocytes, which results in white patches. Classically, vitiligo’s treatments have been considered unsatisfactory and challenging. Recent advances in the knowledge of vitiligo’s pathogenesis have contributed to find better therapeutic options, so that at present many patients find a solution for d...
متن کاملUpdate on skin repigmentation therapies in vitiligo.
Treatment for vitiligo is difficult and prolonged. Nevertheless, at present considerable knowledge accumulated during several decades on the pathogenic mechanisms, revealed important clues for designing new strategies to improve vitiligo depigmentation. With available medical therapies, high repigmentation percentages mostly on facial and neck lesions are achieved, although they are less effect...
متن کاملAssociation of Vitiligo With Tumor Response in Patients With Metastatic Melanoma Treated With Pembrolizumab.
IMPORTANCE Vitiligo is an autoimmune skin disorder that reacts against melanocytes. The association of vitiligo with tumor response in patients with melanoma who undergo immunotherapy has been reported but is still controversial. OBJECTIVE To prospectively evaluate the appearance of vitiligo in patients receiving pembrolizumab, a monoclonal antibody directed against the programmed death cell ...
متن کاملRepigmentation of Tenacious Vitiligo on Apremilast
Vitiligo is a common pigment disorder characterized by acquired loss of function or absence of melanocytes, leading to distinct areas of depigmentation. Physical exam reveals sharply demarcated, depigmented macules or patches on otherwise normal skin. Vitiligo can present at any age, in any skin color. There is no specific serologic marker for diagnosis, but patients often have other autoimmune...
متن کاملRepigmentation of vitiligo with autologous blister-induced epidermal grafts.
Treatment of vitiligo can sometimes be difficult and disappointing. PUVA treatments give fairly good results. However, acral regions like the hands or feet or areas over bony prominences like the elbow, are resistant to PUVA. Blister-induced epidermal grafts have been used to repigment vitiligo skin. This study was carried out on patients with vitiligo areas unresponsive to either PUVA treatmen...
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ژورنال
عنوان ژورنال: Acta Dermato Venereologica
سال: 2019
ISSN: 0001-5555
DOI: 10.2340/00015555-3199